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1. Reduced FOXP3+ regulatory T cells in patients with primary sclerosing cholangitis are associated with IL2RA gene polymorphisms. Sebode, Marcial; Peiseler, Moritz; Franke, Björn; Schwinge, Dorothee; Schoknecht, Tanja; Wortmann, Frederike; Quaas, Alexander; Petersen, Britt-Sabina; et al. Journal of Hepatology vol. 60 issue 5 May, 2014. p. 1010-1016

 Background & AimsRecently, genome wide association studies in primary sclerosing cholangitis (PSC) revealed… (more)

Keywords: Interleukin-2 receptor alpha

DOI: 10.1016/j.jhep.2013.12.027. ISSN: 0168-8278.

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2. MicroRNA expression profiling and functional annotation analysis of their targets in patients with type 1 diabetes mellitus. Takahashi, P.; Xavier, D.J.; Evangelista, A.F.; Manoel-Caetano, F.S.; Macedo, C.; Collares, C.V.A.; Foss-Freitas, M.C.; Foss, M.C.; Rassi, D.M.; Donadi, E.A.; Passos, G.A.; Sakamoto-Hojo, E.T. Gene vol. 539 issue 2 April 15, 2014. p. 213-223

 Type 1 diabetes mellitus (T1DM) results from an autoimmune attack against the insulin-producing… (more)

Keywords: interleukin 2 receptor alpha

DOI: 10.1016/j.gene.2014.01.075. ISSN: 0378-1119.

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3. Insulin-like growth factor 1 (IGF-1) expression is up-regulated in lymphoblastoid cell lines oflithium responsive bipolar disorder patients. Squassina, A.; Costa, M.; Congiu, D.; Manchia, M.; Angius, A.; Deiana, V.; Ardau, R.; Chillotti, C.; Severino, G.; Calza, S.; Del Zompo, M. Pharmacological Research vol. 73 July, 2013. p. 1-7

 Bipolar disorder (BD) is a debilitating psychiatric disease characterized by alternating episodes of… (more)

Keywords: interleukin 2 receptor, alpha

DOI: 10.1016/j.phrs.2013.04.004. ISSN: 1043-6618.

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4. Multiorgan autoimmunity in a Turner syndrome patient with partial monosomy 2q and trisomy 10p. Grossi, A.; Palma, A.; Zanni, G.; Novelli, A.; Loddo, S.; Cappa, M.; Fierabracci, A. Gene vol. 515 issue 2 February 25, 2013. p. 439-443

 Turner syndrome is a condition caused by numeric and structural abnormalities of the… (more)

Keywords: interleukin 2 receptor, alpha chain precursor/CD25

DOI: 10.1016/j.gene.2012.12.007. ISSN: 0378-1119.

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5. Deregulation of signalling pathways in prognostic subtypes of hepatocellular carcinoma: Novel insights from interspecies comparison. Calvisi, D.F.; Frau, M.; Tomasi, M.L.; Feo, F.; Pascale, R.M. BBA - Reviews on Cancer vol. 1826 issue 1 August, 2012. p. 215-237

 Hepatocellular carcinoma is a frequent and fatal disease. Recent researches on rodent models… (more)

Keywords: interleukin 2 receptor, alpha)

DOI: 10.1016/j.bbcan.2012.04.003. ISSN: 0304-419X.

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6. CD45-mediated signaling pathway is involved in Rhizoctonia bataticola lectin (RBL)-induced proliferation and Th1/Th2 cytokine secretion in human PBMC. Pujari, Radha; Eligar, Sachin M.; Kumar, Natesh; Nagre, Nagaraja N.; Inamdar, Shashikala R.; Swamy, Bale M.; Shastry, Padma. Biochemical and Biophysical Research Communications vol. 419 issue 4 March 23, 2012. p. 708-714

 We earlier reported the mitogenic and immunostimulatory activities of Rhizoctonia bataticola lectin (RBL),… (more)

Keywords: interleukin-2 receptor alpha

DOI: 10.1016/j.bbrc.2012.02.084. ISSN: 0006-291X.

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7. A novel assay for detection of hepatitis C virus-specific effector CD4^+ T cells via co-expression of CD25 and CD134. Keoshkerian, E.; Helbig, K.; Beard, M.; Zaunders, J.; Seddiki, N.; Kelleher, A.; Hampartzoumian, T.; Zekry, A.; Lloyd, A.R. Journal of Immunological Methods vol. 375 issue 1-2 January 31, 2012. p. 148-158

 Hepatitis C virus (HCV)-specific CD4^+ effector T cell responses are likely to play… (more)

Keywords: interleukin-2 receptor alpha

DOI: 10.1016/j.jim.2011.10.004. ISSN: 0022-1759.

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8. Soluble interleukin-2 receptor α activation in a Children's Oncology Group randomized trial of interleukin-2 Therapy for Pediatric Acute Myeloid Leukemia. Lange, Beverly J.; Yang, Richard K.; Gan, Jacek; Hank, Jaquelyn A.; Sievers, Eric L.; Alonzo, Todd A.; Gerbing, Robert B.; Sondel, Paul M. Pediatric Blood & Cancer vol. 57 issue 3 September 2011. p. 398-405

 <title type="main">Purpose</title> To assess associations of soluble IL-2 receptor alpha (sIL-2rα) concentration with… (more)

Keywords: soluble interleukin-2 receptor alpha

DOI: 10.1002/pbc.22966. ISSN: 1545-5009.

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9. Rhizoctonia bataticola lectin (RBL) induces mitogenesis and cytokine production in human PBMC via p38 MAPK and STAT-5 signaling pathways. Pujari, R.; Nagre, N.N.; Chachadi, V.B.; Inamdar, S.R.; Swamy, B.M.; Shastry, P. BBA - General Subjects vol. 1800 issue 12 December, 2010. p. 1268-1275

 Background: Rhizoctonia bataticola lectin (RBL), purified from phytopathogenic fungus Rhizoctonia bataticola is highly… (more)

Keywords: Interleukin-2 receptor alpha

DOI: 10.1016/j.bbagen.2010.09.003. ISSN: 0304-4165.

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10. Long-term daclizumab therapy in relapsing-remitting multiple sclerosis. Rojas, Monica A.; Carlson, Noel G.; Miller, Thomas L.; Rose, John W. Therapeutic Advances in Neurological Disorders vol. 2 issue 5 September 2009. p. 291-297

 We performed a retrospective review of side effects and clinical outcomes in relapsing-remitting… (more)

Keywords: interleukin 2 receptor alpha

DOI: 10.1177/1756285609337992. ISSN: 1756-2856.

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11. Hepatic IL-17 responses in human and murine primary biliary cirrhosis. Lan, Ruth Y.Z.; Salunga, Thucydides L.; Tsuneyama, Koichi; Lian, Zhe-Xiong; Yang, Guo-Xiang; Hsu, Willy; Moritoki, Yuki; Ansari, Aftab A.; et al. Journal of Autoimmunity vol. 32 issue 1 February, 2009. p. 43-51

 The emergence of new regulatory and pro-inflammatory immune cell subsets and cytokines dictates… (more)

Keywords: interleukin 2 receptor alpha knockout

DOI: 10.1016/j.jaut.2008.11.001. ISSN: 0896-8411.

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12. Interpretation of interleukin-2 receptor alpha positive cells during induction chemotherapy for adult acute myelogenous leukaemia patients. Min, Woo-Sung; Kim, Hee-Je; Choi, Young; Jeong, Hye-Young; Kim, Chun-Choo. Hematological Oncology vol. 25 issue 2 June 2007. p. 76 - 83

 To correlate clinical outcomes with the expression of interleukin-2 receptor(more)

Keywords: interleukin-2 receptor alpha

DOI: 10.1002/hon.807. ISSN: 0278-0232.

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13. Correction of interleukin-2 gene expression by in vitro zinc addition to mononuclear cells from zinc-deficient human subjects: A specific test for zinc deficiency in humans. Prasad, Ananda S.; Bao, Bin; Beck, Frances W.J.; Sarkar, Fazlul H. Translational Research vol. 148 issue 6 December, 2006. p. 325-333

 A nutritional deficiency of zinc in humans is widespread in the developing world,… (more)

Keywords: Interleukin-2 receptor alpha

DOI: 10.1016/j.trsl.2006.07.008. ISSN: 1931-5244.

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14. IL-2 receptor alpha deficiency and features of primary biliary cirrhosis. Aoki, Christopher A.; Roifman, Chaim M.; Lian, Zhe-Xiong; Bowlus, Christopher L.; Norman, Gary L.; Shoenfeld, Yehuda; Mackay, Ian R.; Eric Gershwin, M. Journal of Autoimmunity vol. 27 issue 1 August, 2006. p. 50-53

 Congenital immune deficiency states have often been valuable experimental models of nature that… (more)

Keywords: interleukin-2 receptor alpha (CD25)

DOI: 10.1016/j.jaut.2006.04.005. ISSN: 0896-8411.

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15. Gene expression analysis of ELF-MF exposed human monocytes indicating the involvement of the alternative activation pathway. Lupke, Madeleine; Frahm, Jana; Lantow, Margareta; Maercker, Christian; Remondini, Daniel; Bersani, Ferdinando; Simkó, Myrtill. BBA - Molecular Cell Research vol. 1763 issue 4 April, 2006. p. 402-412

 This study focused on the cell activating capacity of extremely low frequency magnetic… (more)

Keywords: interleukin 2 receptor alpha

DOI: 10.1016/j.bbamcr.2006.03.003. ISSN: 0167-4889.

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16. Traditional Korean medicine (SCRT) modulate Th1/Th2 specific cytokine production in mice CD4+ T cell. Ko, Eunjung; Rho, Samwoong; Lee, Eui-joon; Seo, Young-Ho; Cho, Chongwoon; Lee, Yongwon; Min, Byung-Il; Shin, Min-Kyu; Hong, Moo-Chang; Bae, Hyunsu. Journal of Ethnopharmacology vol. 92 issue 1 May, 2004. p. 121-128

 Traditional Korea medicine, So-Cheong-Ryong-Tang (SCRT) also called as Xiao-qing-long-tang or Sho-seiru-to, contains eight… (more)

Keywords: Interleukin-2 receptor alpha

DOI: 10.1016/j.jep.2004.02.008. ISSN: 0378-8741.

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17. Influence of thyroxine on serum soluble interleukin-2 receptor alpha levels in thyroid disorders. Żwirska-Korczala, K.; Berdowska, A.; Jochem, J.; Sitkiewicz, A.; Birkner, E.; Polaniak, R.; Jȩdrzejowska-Szypułka, H.; Korzonek-Szlacheta, I. Journal of Clinical Pharmacy & Therapeutics vol. 29 issue 2 April 2004. p. 151-156

  Summary Background:  Activation of cell-mediated immunity by soluble interleukin-2 (more)

Keywords: soluble interleukin-2 receptor alpha

DOI: 10.1111/j.1365-2710.2004.00547.x. ISSN: 0269-4727.

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18. Down-regulation of c-jun N-terminal kinase-activator protein-1 signaling pathway by Ginkgo biloba extract in human peripheral blood T cells. Cheng, Shu-Meng; Yang, Shih-Ping; Ho, Ling-Jun; Tsao, Tien-Ping; Juan, Ting-Yi; Chang, Deh-Ming; Chang, Sun-Yran; Lai, Jenn-Haung. Biochemical Pharmacology vol. 66 issue 4 August 15, 2003. p. 679-689

 The activation of T lymphocytes contributes to inflammatory process of cardiovascular and cerebrovascular… (more)

Keywords: interleukin-2 receptor alpha chain

DOI: 10.1016/S0006-2952(03)00388-5. ISSN: 0006-2952.

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19. Synthetic peptides as putative therapeutic agents in transplantation medicine: application of PEPSCAN to the identification of functional sequences in the extracellular domain of the interleukin-2 receptor beta chain (IL-2Rβ). Dionyssopoulou, Helen; Mouzaki, Athanasia; Slootstra, Jerry; Puijk, Wouter; Meloen, Rob; Cordopatis, Paul; Sotiropoulou, Georgia. Journal of Immunological Methods vol. 241 issue 1-2 July 31, 2000. p. 83-95

 A desired treatment strategy in transplantation medicine is the selective targeting of alloreactive… (more)

Keywords: IL-2Rα, interleukin-2 receptor alpha chain

ISSN: 0022-1759.

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20. Triple helix formation and the antigene strategy for sequence-specific control of gene expression. Praseuth, D.; Guieysse, A.L.; Hélène, C. Biochimica et Biophysica Acta (BBA)/Gene Structure and Expression vol. 1489 issue 1 December 10, 1999. p. 181-206

 Specific gene expression involves the binding of natural ligands to the DNA base… (more)

Keywords: IL-2Rα, Interleukin-2 receptor, alpha subunit

ISSN: 0167-4781.

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21. Induction of cell surface interleukin 2 receptor alpha chain expression on non-T lymphoid leukemia cells. Nakase, K.; Kita, K.; Shirakawa, S.; Tanaka, I.; Tsudo, M. Leukemia Research vol. 18 issue 11 November, 1994. p. 855-859

 We examined nine cases of adult non-T lymphoid leukemia to investigate the cell… (more)

Keywords: Interleukin 2 receptor alpha chain; interleukin 2 receptor alpha chain

DOI: 10.1016/0145-2126(94)90167-8. ISSN: 0145-2126.

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22. Induction of interleukin-2 receptor alpha chain expression on immature acute myelocytic leukemia cells. Nakase, K.; Kita, K.; Anazawa, H.; Hoshino, K.; Shirakawa, S.; Tanaka, I.; Tsudo, M. Leukemia Research vol. 18 issue 4 April, 1994. p. 269-274

 Leukemic cells from 27 adult patients with acute myelocytic leukemia (AML) were investigated… (more)

Keywords: Interleukin-2 receptor alpha chain; [abr] IL-2Rα, interleukin-2 receptor alpha chain

DOI: 10.1016/0145-2126(94)90029-9. ISSN: 0145-2126.

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23. Interleukin-2 receptor alpha chain on acute myelocytic leukemia cells is involved in cell-to-cell interactions. Nakase, K.; Kita, K.; Otsuji, A.; Anazawa, H.; Shirakawa, S.; Nasu, K.; Dohy, H.; Tsutani, H.; Tanaka, I. Leukemia Research vol. 17 issue 1 January, 1993. p. 17-21

 Leukemic cells from 21 of 197 adult patients with de novo acute myelocytic… (more)

Keywords: Interleukin-2 receptor alpha chain; [abr] IL-2Rα, interleukin-2 receptor alpha chain

DOI: 10.1016/0145-2126(93)90136-9. ISSN: 0145-2126.

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24. Activation of HIV-enhancer binding activity by mild detergents in human T cells. Harel-Bellan, A.; Korner, M.; Brini, A.T.; Ferris, D.; Farrar, W.L. Biochemical and Biophysical Research Communications vol. 162 issue 1 July 14, 1989. p. 238-243

 Binding activity to the HIV enhancer, a sequence highly homologous to the NF-KB… (more)

Keywords: interleukin 2 receptor alpha chain

DOI: 10.1016/0006-291X(89)91987-6. ISSN: 0006-291X.

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