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[1] [2]

1. Comparison of alkylamide yield in ethanolic extracts prepared from fresh versus dry Echinacea purpurea utilizing HPLC–ESI-MS. Spelman, Kevin; Wetschler, Matthew H.; Cech, Nadja B. Journal of Pharmaceutical and Biomedical Analysis vol. 49 issue 5 July 12, 2009. p. 1141-1149

 Echinacea purpurea (L.) Moench, a top selling botanical medicine, is currently of considerable… (more)

Keywords: isomers of dodeca-2,4,8,10-tetraenoic acid isobutylamide; Isobutylamide

DOI: 10.1016/j.jpba.2009.02.011. ISSN: 0731-7085.

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2. High performance liquid chromatography/electrospray ionization mass spectrometry for simultaneous analysis of alkamides and caffeic acid derivatives from Echinacea purpurea extracts. Cech, Nadja B.; Eleazer, Maqueita S.; Shoffner, Lawresa T.; Crosswhite, Mark R.; Davis, Amanda C.; Mortenson, Ashley M. Journal of Chromatography A vol. 1103 issue 2 January 27, 2006. p. 219-228

 Extracts of the plant Echinacea purpurea are widely used for medicinal purposes. Effective… (more)

Keywords: Isobutylamides

DOI: 10.1016/j.chroma.2005.11.008. ISSN: 0021-9673.

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3. Amides from Achillea species and Leucocyclus formosus. Greger, H.; Grenz, M.; Bohlmann, F. Phytochemistry vol. 20 issue 11 1981. p. 2579-2581

Keywords: isobutylamides

DOI: 10.1016/0031-9422(81)83098-1. ISSN: 0031-9422.

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4. An imidazole alkaloid and other constituents from Pilocarpus trachyllophus. Andrade-Neto, Manoel; Mendes, Paulo Henriques; Silveira, Edilberto Rocha. Phytochemistry vol. 42 issue 3 June, 1996. p. 885-887

 Roots of Pilocarpus trachyllophus yielded (−)-episesamin, hesperidin, tridecan-2-one, 1-hydroxy-tridecan-2-one,N -isobutyl-deca-2(E),4(E)-dienamide, pilocarpine and a… (more)

Keywords: isobutylamide

ISSN: 0031-9422.

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5. Neue acetylenverbindungen aus Leucanthemum-arten und revision der struktur eines germacranolids. Bohlmann, F.; Fritz, U.; Dutta, L. Phytochemistry vol. 19 issue 5 1980. p. 841-844

 The investigation of three Leucanthemum species afforded, in addition to known compounds, two… (more)

Keywords: new isobutylamide

DOI: 10.1016/0031-9422(80)85123-5. ISSN: 0031-9422.

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6. Chemical Constituents from the Leaves of Zanthoxylum Schinifolium. Cheng, Ming‐Jen; Yang, Cheng‐Hui; Lin, Wen‐Yu; Lin, Wei‐Yu; Tsai, Ian‐Lih; Chen, Ih‐Sheng. Journal of the Chinese Chemical Society vol. 49 issue 1 February 2002. p. 125-128

  cis-Fagaramide (1), a new amide, together with fifty known compounds, have been… (more)

Keywords: Isobutylamide

DOI: 10.1002/jccs.200200021. ISSN: 0009-4536.

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7. Isobutylamides from the fruit of Zanthoxylum integrifoliolum. Chen, Ih-Sheng; Chen, Tzu-Li; Lin, Wei-Yu; Tsai, Ian-Lih; Chen, Yu-Chang. Phytochemistry vol. 52 issue 2 September, 1999. p. 357-360

 Investigation of the fruit of Zanthoxylum integrifoliolum led to the isolation of three… (more)

Keywords: Isobutylamides

ISSN: 0031-9422.

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8. Piscicidal properties of piperovatine from Piper piscatorum (Piperaceae). McFerren, Marcus A.; Rodriguez, Eloy. Journal of Ethnopharmacology vol. 60 issue 2 March, 1998. p. 183-187

 Extraction of the roots of the Amazonian medicinal plant, Piper piscatorum Trelease and… (more)

Keywords: Isobutylamides

ISSN: 0378-8741.

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9. EVIDENCE FOR AN ISOBUTYLAMIDE ASSOCIATED WITH HOST-PLANT RESISTANCE TO WESTERN FLOWER THRIPS, Frankliniella occidentalis, IN CHRYSANTHEMUM. TSAO, RONG; MARVIN, CHRIS H.; BROADBENT, A. BRUCE; FRIESEN, MARTINA; ALLEN, WAYNE R.; MCGARVEY, BRIAN D. Journal of Chemical Ecology vol. 31 issue 1 January 2005. p. 103 - 110

  Bioassay-directed fractionation of extracts of chrysanthemum leaves using a choice test permitted… (more)

Keywords: isobutylamide

DOI: 10.1007/s10886-005-0977-1. ISSN: 0098-0331.

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10. Echinacea metabolism and drug interactions: The case for standardization of a complementary medicine. Toselli, Francesca; Matthias, Anita; Gillam, Elizabeth M.J. Life Sciences vol. 85 issue 3-4 July 15, 2009. p. 97-106

 The herbal medicine, Echinacea, is used for treatment and prevention of upper respiratory… (more)

Keywords: Isobutylamides

DOI: 10.1016/j.lfs.2009.04.023. ISSN: 0024-3205.

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11. Diacetylenic isobutylamides of Echinacea: synthesis and natural distribution. Wu, Lankun; Bae, Jaehoon; Kraus, George; Wurtele, Eve Syrkin. Phytochemistry vol. 65 issue 17 September, 2004. p. 2477-2484

 The syntheses of three diacetylenic isobutylamides of Echinacea angustifolia have been achieved… (more)

Keywords: Diacetylenic isobutylamides

DOI: 10.1016/j.phytochem.2004.06.027. ISSN: 0031-9422.

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12. A sensitive LC-MS/MS method for the quantitative analysis of the Echinacea purpurea constituent undeca-2-ene-8,10-diynoic acid isobutylamide in human plasma. Goey, A.K.L.; Sparidans, R.W.; Meijerman, I.; Rosing, H.; Schellens, J.H.M.; Beijnen, J.H. Journal of Chromatography B vol. 879 issue 1 January 1, 2011. p. 41-48

 Echinacea purpurea is one of the most popular herbal medicines and is known… (more)

Keywords: Undeca-2-ene-8,10-diynoic acid isobutylamide; Isobutylamide

DOI: 10.1016/j.jchromb.2010.11.007. ISSN: 1570-0232.

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13. In vitro neuropharmacological evaluation of piperovatine, an isobutylamide from Piper piscatorum (Piperaceae). McFerren, Marcus A.; Cordova, Daniel; Rodriguez, Eloy; Rauh, James J. Journal of Ethnopharmacology vol. 83 issue 3 December, 2002. p. 201 - 207

 Piperovatine, a sialogogic, piscicidal, and buccal local anesthesia producing isobutyl amide from the… (more)

Keywords: Isobutyl-amide

ISSN: 0378-8741.

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14. Echinacea and its alkylamides: Effects on the influenza A-induced secretion of cytokines, chemokines, and PGE2 from RAW 264.7 macrophage-like cells. Cech, N.B.; Kandhi, V.; Davis, J.M.; Hamilton, A.; Eads, D.; Laster, S.M. International Immunopharmacology vol. 10 issue 10 October, 2010. p. 1268-1278

 The goal of this study was to determine whether extracts and isolated alkylamides… (more)

Keywords: Isobutylamide

DOI: 10.1016/j.intimp.2010.07.009. ISSN: 1567-5769.

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15. Isobutylamide numbing agents of toothache grass, Ctenium aromaticum. Gamboa-Leon, Rubi; Scott Chilton, William. Biochemical Systematics and Ecology vol. 28 issue 10 December, 2000. p. 1019-1021

Keywords: Isobutylamides

ISSN: 0305-1978.

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16. Isobutylamides and Coumarins from Melicope melanophloia. Latif, Zahid; Hartley, T.G.; Rice, Martin J.; Waigh, Roger D.; Waterman, Peter G. Biochemical Systematics and Ecology vol. 26 issue 4 June, 1998. p. 467-468

Keywords: isobutylamides

ISSN: 0305-1978.

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17. Biosynthetically simple C18-alkamides from Achillea species. Greger, Harald; Hofer, Otmar; Werner, Andreas. Phytochemistry vol. 26 issue 8 1987. p. 2235-2242

 The petrol-diethyl ether extracts of the underground parts of Achillea lycaonica and A.… (more)

Keywords: isobutylamides

DOI: 10.1016/S0031-9422(00)84690-7. ISSN: 0031-9422.

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18. A mosquito larvicide in Spilanthes mauritiana. Jondiko, I.J.O. Phytochemistry vol. 25 issue 10 1986. p. 2289-2290

 The methanol extract of fresh vegetative aerial parts of Spilanthes mauritiana afforded, after… (more)

Keywords: N-isobutylamide.

DOI: 10.1016/S0031-9422(00)81681-7. ISSN: 0031-9422.

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19. An amide from salmea scandens. Herz, W.; Kulanthaivel, P. Phytochemistry vol. 24 issue 1 1985. p. 173-174

Costunolide and the isobutylamides of 2E,4E,8Z,10Z- and 2E,4E,8Z,10E-dodeca-2,4,8,10-tetraenoic acid were isolated from the roots of Salmea scandens.

Keywords: isobutylamides

DOI: 10.1016/S0031-9422(00)80830-4. ISSN: 0031-9422.

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20. Chemical Constituents from the Root Bark of Formosan Zanthoxylum Ailanthoides. Cheng, Ming‐Jen; Tsai, Ian‐Lih; Chen, Ih‐Sheng. Journal of the Chinese Chemical Society vol. 50 issue 6 December 2003. p. 1241-1246

 Two new N-isobutylamides, hydroxy lanyuamide I (1) and hydroxy lanyuamide II (2),… (more)

Keywords: Isobutylamide

DOI: 10.1002/jccs.200300178. ISSN: 0009-4536.

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21. Role for PPARγ in IL-2 inhibition in T cells by Echinacea-derived undeca-2E-ene-8,10-diynoic acid isobutylamide. Spelman, K.; Iiams-Hauser, K.; Cech, N.B.; Taylor, E.W.; Smirnoff, N.; Wenner, C.A. International Immunopharmacology vol. 9 issue 11 October, 2009. p. 1260-1264

 Certain fatty acid amides from Echinacea spp. have demonstrated moderate to high cannabinoid… (more)

Keywords: Undeca-2E-ene-8,10-diynoic acid isobutylamide

DOI: 10.1016/j.intimp.2009.08.009. ISSN: 1567-5769.

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22. New amides fromSpilanthes oleracea. Greger, Harald; Hofer, Otmar; Werner, Andreas. Monatshefte für Chemie Chemical Monthly vol. 116 issue 2 February 1985. p. 273 - 277

  In addition to the well known affinin [=spilanthol, (2E,6Z,8E)-deca-2,6,8-trienoic acid isobutylamide(more)

Keywords: Acetylenic isobutylamides

DOI: 10.1007/BF00798463. ISSN: 0026-9247.

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23. (E,E)-N-Isobutyl-2,4-octadienamide from Piper marginatum. de Oliveira Santos, Bárbara Viviana; de Oliveira Chaves, Maria Célia. Biochemical Systematics and Ecology vol. 27 issue 1 January, 1999. p. 113-114

Keywords: Isobutylamides

ISSN: 0305-1978.

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24. Acetylenic 2-phenylethylamides and new isobutylamides from Acmella oleracea (L.) R. K. Jansen, a Brazilian spice with larvicidal activity on Aedes aegypti. Simas, N.K.; Dellamora, E.d.C.L.; Schripsema, J.; Lage, C.L.S.; Filho, A.M.d.O.; Wessjohann, L.; Porzel, A.; Kuster, R.M. Phytochemistry Letters vol. 6 issue 1 February, 2013. p. 67-72

 Ethanol extract obtained from dried leaves of Acmella oleracea afforded after a liquid/liquid… (more)

Keywords: Isobutylamides

DOI: 10.1016/j.phytol.2012.10.016. ISSN: 1874-3900.

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25. Zanthoxylum capense constituents with antimycobacterial activity against Mycobacterium tuberculosis in vitro and ex vivo within human macrophages. Luo, Xuan; Pires, David; Aínsa, José A.; Gracia, Begoña; Duarte, Noélia; Mulhovo, Silva; Anes, Elsa; Ferreira, Maria-José U. Journal of Ethnopharmacology vol. 146 issue 1 March 7, 2013. p. 417-422

 Ethnopharmacological relevanceZanthoxylum capense Thunb. (Rutaceae) is a medicinal plant traditionally used in Mozambique… (more)

Keywords: N-isobutylamide

DOI: 10.1016/j.jep.2013.01.013. ISSN: 0378-8741.

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26. An amide from fruits of Piper nigrum. Siddiqui, Bina S.; Begum, Sabira; Gulzar, Tahsin; Noor, Farhat; Noor, Fatima. Phytochemistry vol. 45 issue 8 August, 1997. p. 1617-1619

 A new amide, N-isobutyl amide of octadeca-trans-2-cis-4-dienoic acid has been isolated from the… (more)

Keywords: N-isobutylamide of octadeca-trans-2-cis-4-dienoic acid

ISSN: 0031-9422.

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27. Pharmacokinetics and Tissue Distribution of Dodeca-2E,4E,8E,10E/Z-tetraenoic Acid Isobutylamides after Oral Administration in Rats. Woelkart, Karin; Frye, Reginald F.; Derendorf, Hartmut; Bauer, Rudolf; Butterweck, Veronika. Planta Medica vol. 75 issue 12 2009. p. 1306-1313

 The present study investigated the pharmacokinetics and tissue distribution of dodeca-2E,4E,8(more)

Keywords: Echinacea; Asteraceae; dodeca‐2E,4E,8E,10E/Z‐tetraenoic acid isobutylamides; bioavailability; pharmacokinetics; tissue distribution; LC‐MS

DOI: 10.1055/s-0029-1185631. ISSN: 0032-0943.

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28. Pharmacokinetics and Tissue Distribution of Dodeca-2E,4E,8E,10E/Z-tetraenoic Acid Isobutylamides after Oral Administration in Rats. Woelkart, Karin; Frye, Reginald F.; Derendorf, Hartmut; Bauer, Rudolf; Butterweck, Veronika. Planta Medica vol. 75 issue 12 2009. p. 1306-1313

 The present study investigated the pharmacokinetics and tissue distribution of dodeca-2E,4E,8(more)

Keywords: dodeca‐2E,4E,8E,10E/Z‐tetraenoic acid isobutylamides

DOI: 10.1055/s-0029-1185631. ISSN: 0032-0943.

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29. The Traditional Medicine Spilanthes acmella, and the Alkylamides Spilanthol and Undeca-2E-ene-8,10-diynoic Acid Isobutylamide, Demonstrate In Vitro and In Vivo Antimalarial Activity. Spelman, Kevin; Depoix, Delphine; McCray, Megan; Mouray, Elisabeth; Grellier, Philippe. Phytotherapy Research vol. 25 issue 7 July 2011. p. 1098-1101

  Spilanthes spp. are used as traditional herbal medicines in Africa and India… (more)

Keywords: deca‐2E,6Z,8E‐trienoic acid isobutylamide

DOI: 10.1002/ptr.3395. ISSN: 0951-418X.

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30. The bioanalysis of the major Echinacea purpurea constituents dodeca-2E,4E,8Z,10E/Z-tetraenoic acid isobutylamides in human plasma using LC-MS/MS. Goey, A.K.L.; Rosing, H.; Meijerman, I.; Sparidans, R.W.; Schellens, J.H.M.; Beijnen, J.H. Journal of Chromatography B vol. 902 August 1, 2012. p. 151-156

 Alkylamides are a group of active components of the widely used herb Echinacea… (more)

Keywords: Dodeca-2E,4E,8Z,10E/Z-tetraenoic acid isobutylamides

DOI: 10.1016/j.jchromb.2012.06.022. ISSN: 1570-0232.

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