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1. Preferential inducibility of CYP1A1 and CYP1A2 by TCDD: Differential regulation in primary human hepatocytes versus transformed human cells. Zhang, Zhi-Yi; Pelletier, Robert D.; Wong, Y. Nancy; Sugawara, Michiko; Zhao, Nanding; Littlefield, Bruce A. Biochemical and Biophysical Research Communications vol. 341 issue 2 March 10, 2006. p. 399-407

 Cytochrome P4501A1 (CYP1A1) induction, a marker of aryl hydrocarbon (Ah) receptor activation, has… (more)

Keywords: Cytochrome P450; 2,3,7,8-Tetrachlorodibenzo-p-dioxin; Aryl hydrocarbon receptor; Human primary hepatocytes; Protein synthesis inhibitor; Warfarin hydroxylation

DOI: 10.1016/j.bbrc.2005.12.203. ISSN: 0006-291X.

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2. Mechanical properties of sensory and supporting cells in the organ of Corti of the guinea pig cochlea – study by atomic force microscopy. Sugawara, Michiko; Ishida, Yuya; Wada, Hiroshi. Hearing Research vol. 192 issue 1-2 June, 2004. p. 57-64

 Mammalian hearing is refined by amplification of the motion of the cochlear partition.… (more)

Keywords: IHC, inner hair cell; OHC, outer hair cell; AFM, atomic force microscopy; Hensen's cells; Deiters' cells; Inner hair cells; Mechanical properties; Atomic force microscopy

DOI: 10.1016/j.heares.2004.01.014. ISSN: 0378-5955.

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3. Imaging of the cortical cytoskeleton of guinea pig outer hair cells using atomic force microscopy

This study was presented at the 26th Midwinter Research Meeting of the Association for Research in Otolaryngology in February 2003.

. Wada, Hiroshi; Kimura, Kei; Gomi, Takashi; Sugawara, Michiko; Katori, Yukio; Kakehata, Seiji; Ikeda, Katsuhisa; Kobayashi, Toshimitsu. Hearing Research vol. 187 issue 1-2 January, 2004. p. 51-62

 Mammalian outer hair cells (OHCs) are known to respond to acoustical stimulation with… (more)

Keywords: Outer hair cell; Atomic force microscope; Cortical lattice; Actin filament; Spectrin cross-link

DOI: 10.1016/S0378-5955(03)00334-4. ISSN: 0378-5955.

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4. Relationship between the local stiffness of the outer hair cell along the cell axis and its ultrastructure observed by atomic force microscopy. Wada, Hiroshi; Usukura, Hiroto; Sugawara, Michiko; Katori, Yukio; Kakehata, Seiji; Ikeda, Katsuhisa; Kobayashi, Toshimitsu. Hearing Research vol. 177 issue 1-2 March, 2003. p. 61-70

 As electromotility may arise from a conformational change of the molecules’ ‘protein motors’,… (more)

Keywords: Ultrastructure; Outer hair cell; Lateral wall; Cortical lattice; Actin filament; Atomic force microscopy

ISSN: 0378-5955.

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5. Local mechanical properties of guinea pig outer hair cells measured by atomic force microscopy

This study was presented at the 25th Midwinter Research Meeting of the Association for Research in Otolaryngology in January 2002.

. Sugawara, Michiko; Ishida, Yuya; Wada, Hiroshi. Hearing Research vol. 174 issue 1-2 December, 2002. p. 222-229

 In this study, mechanical properties of guinea pig outer hair cells (OHCs) were… (more)

Keywords: Outer hair cell; Guinea pig; Local mechanical property; Atomic force microscopy

ISSN: 0378-5955.

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6. Measurement of guinea pig basilar membrane using computer-aided three-dimensional reconstruction system. Wada, Hiroshi; Sugawara, Michiko; Kobayashi, Toshimitsu; Hozawa, Koji; Takasaka, Tomonori. Hearing Research vol. 120 issue 1-2 June, 1998. p. 1-6

 Cochleas are known to have the ability to analyze a frequency widely, and… (more)

Keywords: Computer-aided three-dimensional reconstruction; Guinea pig; Basilar membrane; Cochlea; Frequency-position

ISSN: 0378-5955.

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7. Analysis of elastic properties of outer hair cell wall using shell theory

This study was presented at the 24th Midwinter Research Meeting of the Association for Research in Otolaryngology, February 2001.

. Sugawara, Michiko; Wada, Hiroshi. Hearing Research vol. 160 issue 1-2 October, 2001. p. 63-72

 In this study, the mechanical properties of the lateral wall of the outer… (more)

Keywords: Outer hair cell; Shell model; Elastic property; Numerical analysis; OHC, outer hair cell

ISSN: 0378-5955.

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8. Blood-Brain Barrier Produces Significant Efflux of L-Aspartic Acid but Not D-Aspartic Acid. Hosoya, Ken-ichi; Sugawara, Michiko; Asaba, Hiroshi; Terasaki, Tetsuya. Journal of Neurochemistry vol. 73 issue 3 September 1, 1999. p. 1206-1211

  Abstract : The brain efflux index method has been used to clarify… (more)

Keywords: Efflux transport; L-Aspartic acid; D-Aspartic acid; L-Glutamic acid; Blood-brain barrier.

DOI: 10.1046/j.1471-4159.1999.0731206.x. ISSN: 0022-3042.

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9. Preferential inducibility of CYP1A1 and CYP1A2 by TCDD: Differential regulation in primary human hepatocytes versus transformed human cells. Zhang, Zhi-Yi; Pelletier, Robert D.; Wong, Y. Nancy; Sugawara, Michiko; Zhao, Nanding; Littlefield, Bruce A. Biochemical and Biophysical Research Communications vol. 341 issue 2 March 10, 2006. p. 399-407

 Cytochrome P4501A1 (CYP1A1) induction, a marker of aryl hydrocarbon (Ah) receptor activation, has… (more)

Keywords: Cytochrome P450; 2,3,7,8-Tetrachlorodibenzo-p-dioxin; Aryl hydrocarbon receptor; Human primary hepatocytes; Protein synthesis inhibitor; Warfarin hydroxylation

DOI: 10.1016/j.bbrc.2005.12.203. ISSN: 0006-291X.

More Like This

10. Generation of metabolically functioning hepatocytes from human pluripotent stem cells by FOXA2 and HNF1α transduction. Takayama, Kazuo; Inamura, Mitsuru; Kawabata, Kenji; Sugawara, Michiko; Kikuchi, Kiyomi; Higuchi, Maiko; Nagamoto, Yasuhito; Watanabe, Hitoshi; et al. Journal of Hepatology vol. 57 issue 3 September, 2012. p. 628-636

 Background & AimsHepatocyte-like cells differentiated from human embryonic stem cells (hESCs) and induced… (more)

Keywords: FOXA2; HNF1α; Hepatocytes; Adenovirus; Drug screening; Drug metabolism; hESCs; hiPSCs

DOI: 10.1016/j.jhep.2012.04.038. ISSN: 0168-8278.

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