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1. Pharmacological consequences of oxidative stress in ocular tissues. Ohia, Sunny E.; Opere, Catherine A.; LeDay, Angela M. Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis vol. 579 issue 1-2 November 11, 2005. p. 22-36

 The eye is a unique organ because of its constant exposure to radiation,… (more)

Keywords: Ocular tissues; Oxidative stress; Free radicals

DOI: 10.1016/j.mrfmmm.2005.03.025. ISSN: 0027-5107.

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2. Super CitriMax (HCA-SX) attenuates increases in oxidative stress, inflammation, insulin resistance, and body weight in developing obese Zucker rats. Asghar, Mohammad; Monjok, Emmanuel; Kouamou, Ghislaine; Ohia, Sunny E.; Bagchi, Debasis; Lokhandwala, Mustafa F. Molecular and Cellular Biochemistry vol. 304 issue 1-2 October 2007. p. 93 - 99

  Super CitriMax (HCA-SX) is a novel calcium/potassium salt of (−)-hydroxycitric acid extracted… (more)

Keywords: Metabolic syndrome; Syndrome X; Hypertension; HOMA; Blood pressure; Garcinia cambogia

DOI: 10.1007/s11010-007-9489-3. ISSN: 0300-8177.

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3. Safety and mechanism of appetite suppression by a novel hydroxycitric acid extract (HCA-SX). Ohia, Sunny E.; Opere, Catherine A.; LeDay, Angela M.; Bagchi, Manashi; Bagchi, Debasis; Stohs, Sidney J. Molecular and Cellular Biochemistry vol. 238 issue 1-2 September 2002. p. 89-103

 A growing body of evidence demonstrates the efficacy of Garcinia cambogia-derived natural (–)-hydroxycitric… (more)

Keywords: Garcinia cambogia; (–)-Hydroxycitric acid; fluoxetine; clomipramine; rat brain cortex; serotonin release; appetite; acute oral toxicity; acute dermal toxicity; primary dermal irritation; primary eye irritation

ISSN: 0300-8177.

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4. Physico-chemical properties of a novel (—)-hydroxycitric acid extract and its effect on body weight, selected organ weights, hepatic lipid peroxidation and DNA fragmentation, hematology and clinical chemistry, and histopathological changes over a period of 90 days. Shara, Michael; Ohia, Sunny E.; Schmidt, Robert E.; Yasmin, Taharat; Zardetto-Smith, Andrea; Kincaid, Anthony; Bagchi, Manashi; Chatterjee, Archana; Bagchi, Debasis; Stohs, Sidney J. Molecular and Cellular Biochemistry vol. 260 issue 1 May 2004. p. 171 - 186

  Garcinia cambogia-derived (—)-hydroxycitric acid (HCA) is a popular and natural supplement… (more)

Keywords: Garcinia cambogia; (—)-Hydroxycitric acid; 90-day toxicity study; body and selected organ weights; hepatic lipid peroxidation and DNA damage; hematology and clinical chemistry; histopathology

DOI: 10.1023/B:MCBI.0000026069.53960.75. ISSN: 0300-8177.

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5. Effect of Hydrogen Sulfide on Sympathetic Neurotransmission and Catecholamine Levels in Isolated Porcine Iris-Ciliary Body. Kulkarni, Kaustubh H.; Monjok, Emmanuel M.; Zeyssig, Robert; Kouamou, Ghislaine; Bongmba, Odelia N.; Opere, Catherine A.; Njie, Ya Fatou; Ohia, Sunny E. Neurochemical Research vol. 34 issue 3 March 2009. p. 400 - 406

  In the present study, we investigated the pharmacological action of hydrogen sulfide… (more)

Keywords: Hydrogen sulfide; Catecholamines; Anterior uvea; Neurotransmission

DOI: 10.1007/s11064-008-9793-7. ISSN: 0364-3190.

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6. Prejunctional α2-Adrenoceptors and Peroxide-Induced Potentiation of Norepinephrine Release from the Bovine Iris. Opere, Catherine A.; Ohia, Sunny E. Neurochemical Research vol. 23 issue 8 August 1998. p. 1093-1098

 Peroxides can enhance field-stimulated [3H];norepinephrine ([3H];NE) release in isolated irides from several mammalian… (more)

Keywords: Hydrogen peroxide; α2-adrenoceptors; bovine iris; norepinephrine release; yohimbine

ISSN: 0364-3190.

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7. Effect of Isoprostanes on Sympathetic Neurotransmission in the Human Isolated Iris-Ciliary Body. Awe, S. Olubusayo; Opere, Catherine A.; Harris, Lydia C.; Uketui, Afam J.; Ohia, Sunny E. Neurochemical Research vol. 25 issue 4 April 2000. p. 491-496

 Isoprostanes (IsoP’s) are prostaglandin-like compounds that are derived from free-radical catalyzed peroxidation of… (more)

Keywords: Isoprostanes; thromboxanes; norepinephrine; human; iris-ciliary body

ISSN: 0364-3190.

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8. Effect of Inhibition of Cyclooxygenase on Pre- and Postjunctional Actions of Peroxides in the Iris-Ciliary Body. Graham, Jennifer; Awe, S. Olubusayo; LeDay, Angela M.; Rice, Justin C.; Ramos, Gretel; Harris, Lydia C.; Opere, Catherine A.; Ohia, Sunny E. Neurochemical Research vol. 25 issue 4 April 2000. p. 519-525

 In the present study, we investigated the effect of inhibition of cyclooxygenase (COX)… (more)

Keywords: Hydrogen peroxide; iris-ciliary body; flurbiprofen; norepinephrine release; carbachol

ISSN: 0364-3190.

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9. Human, Bovine, and Rabbit Retinal Glutamate-Induced [3H];D-Aspartate Release: Role in Excitotoxicity. Ohia, Sunny E.; Opere, Catherine A.; Awe, S. Olubusayo; Adams, Leo; Sharif, Najam A. Neurochemical Research vol. 25 issue 6 June 2000. p. 853-860

 The pharmacological basis of glutamate-induced [^3H];D-aspartate release was investigated in isolated human, bovine… (more)

Keywords: Retina; glutamate; aspartate; polyamines; receptors; excitotoxicity

ISSN: 0364-3190.

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10. Effect of Peroxides on [3H];d-Aspartate Release from Bovine Isolated Retinae. LeDay, Angela M.; Awe, Sunday O.; Kulkarni, Kaustubh; Harris, Lydia C.; Opere, Catherine; Dash, Alekha; Ohia, Sunny E. Neurochemical Research vol. 29 issue 4 April 2004. p. 811-818

 In the present study, we investigated the effect of naturally occurring and synthetic… (more)

Keywords: Hydrogen peroxide; retina, aspartate release; antioxidants; catalase

ISSN: 0364-3190.

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11. Dual Effect of Isoprostanes on the Release of [3H]D-Aspartate from Isolated Bovine Retinae: Role of Arachidonic Acid Metabolites. Opere, Catherine A.; Zheng, Wei Dong; Huang, Jifan; Adewale, Adeniran; Kruglet, Michael; Ohia, Sunny E. Neurochemical Research vol. 30 issue 1 January 2005. p. 129 - 137

  The effect of 8-isoprostanes on potassium (K+)-depolarization-evoked release of [3H]D-aspartate from bovine… (more)

Keywords: Aspartate; excitatory; inhibitory; isoprostanes; receptors; retina

DOI: 10.1007/s11064-004-9694-3. ISSN: 0364-3190.

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12. Regulation of Norepinephrine Release from Isolated Bovine Irides by Histamine. Kulkarni, Kaustubh H.; Opere, Catherine A.; LeDay, Angela M.; Shara, Mohd A.; Ohia, Sunny E. Neurochemical Research vol. 31 issue 7 July 2006. p. 891 - 897

  In the present study, we investigated the effect of histamine on sympathetic… (more)

Keywords: Bovine irides; Norepinephrine release; Histamine; Prejunctional histamine receptors

DOI: 10.1007/s11064-006-9093-z. ISSN: 0364-3190.

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13. Regulation of [3H] d-Aspartate Release from Mammalian Isolated Retinae by Hydrogen Sulfide. Opere, Catherine A.; Monjok, Emmanuel M.; Kulkarni, Kaustubh H.; Njie, Ya Fatou; Ohia, Sunny E. Neurochemical Research vol. 34 issue 11 November 2009. p. 1962 - 1968

  Hydrogen sulfide (H2S), can produce pharmacological effects on neural and non-neural tissues… (more)

Keywords: Hydrogen sulfide; [3H] d-aspartate; Retina; Neurotransmission

DOI: 10.1007/s11064-009-9984-x. ISSN: 0364-3190.

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14. Effect of Hydrogen Sulfide on Cyclic AMP Production in Isolated Bovine and Porcine Neural Retinae. Njie-Mbye, Ya Fatou; Bongmba, Odelia Y. N.; Onyema, Chinwe C.; Chitnis, Abhishek; Kulkarni, Madhura; Opere, Catherine A.; LeDay, Angela M.; Ohia, Sunny E. Neurochemical Research vol. 35 issue 3 March 2010. p. 487 - 494

  Hydrogen sulfide (H2S) has been reported to exert pharmacological effects on neural… (more)

Keywords: Hydrogen sulfide; Cyclic AMP; Retina; Sodium sulfide; Sodium hydrosulfide

DOI: 10.1007/s11064-009-0085-7. ISSN: 0364-3190.

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15. Role of Prostanoid Production and Receptors in the Regulation of Retinal Endogenous Amino Acid Neurotransmitters by 8-Isoprostaglandin E2, Ex Vivo. Zhao, Min; Destache, Christopher J.; Ohia, Sunny E.; Opere, Catherine A. Neurochemical Research vol. 34 issue 12 December 2009. p. 2170 - 2180

  The role of enzymes and receptors of the prostanoid pathway in the… (more)

Keywords: Retina; 8-Isoprostaglandin E2; Amino acid neurotransmitters; Prostanoid synthesis; Prostanoid receptors; Glutamate; Glutamine; Glycine

DOI: 10.1007/s11064-009-0013-x. ISSN: 0364-3190.

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16. Endogenous Production of Hydrogen Sulfide in Isolated Bovine Eye. Kulkarni, Madhura; Njie-Mbye, Ya Fatou; Okpobiri, Ikechukwu; Zhao, Min; Opere, Catherine A.; Ohia, Sunny E. Neurochemical Research vol. 36 issue 8 August 2011. p. 1540 - 1545

  Hydrogen sulfide (H2S) is a novel gasotransmitter with physiological and pathological functions… (more)

Keywords: Hydrogen sulfide; Bovine retina; Cystathionine β-synthase (CBS); Cystathionine γ-lyase (CSE)

DOI: 10.1007/s11064-011-0482-6. ISSN: 0364-3190.

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17. Inhibitory action of hydrogen sulfide on muscarinic receptor-induced contraction of isolated porcine irides. Monjok, Emmanuel M.; Kulkarni, Kaustubh H.; Kouamou, Ghislaine; McKoy, Marshalyn; Opere, Catherine A.; Bongmba, Odelia N.; Njie, Ya Fatou; Ohia, Sunny E. Experimental Eye Research vol. 87 issue 6 December 10, 2008. p. 612-616

 We investigated the pharmacological actions of hydrogen sulfide (H2S) using sodium hydrosulfide (NaHS)… (more)

Keywords: hydrogen sulfide; porcine irides; relaxation; sodium hydrosulfide; sodium sulfide; cystathionine β-synthase; cystathionine γ-lyase; H2S; hydrogen sulfide; Na2S; sodium sulfide; CSE; cystathionine γ-lyase; CBS; cystathionine β-synthase; PAG; propargylglycine; BCA; β-cyanoalanine; AOA; aminooxyacetic acid; HOA; hydroxylamine; l-NAME; l-nitroarginine methyl ester

DOI: 10.1016/j.exer.2008.09.011. ISSN: 0014-4835.

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18. [3H]-Serotonin Release from Bovine Iris-ciliary Body: Pharmacology of Prejunctional Serotonin (5-HT7) Autoreceptors. Harris, Lydia C; Awe, S. Olubusayo; Opere, Catherine A.; LeDay, Angela M.; Ohia, Sunny E.; Sharif, Najam A. Experimental Eye Research vol. 73 issue 1 July, 2001. p. 59-67

 In the present study, we investigated the pharmacological characteristics of electrically stimulated [3H]-serotonin… (more)

Keywords: serotonin; receptors; iris-ciliary body; human; bovine

DOI: 10.1006/exer.2001.1012. ISSN: 0014-4835.

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19. Role of Intracellular Calcium in Peroxide-Induced Potentiation of Norepinephrine Release from Bovine Isolated Irides. Opere, Catherine A.; Ohia, Sunny E. General Pharmacology vol. 31 issue 5 November, 1998. p. 793-798

 BAPTA AM (10 μM), thapsigargin (10 μM), ruthenium red (30 μM) and oligomycin… (more)

Keywords: Hydrogen peroxide; intracellular calcium; bovine iris; norepinephrine release; calcium channel antagonists; oxidative stress

ISSN: 0306-3623.

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20. Mechanism of action of hydrogen sulfide on cyclic AMP formation in rat retinal pigment epithelial cells. Njie-Mbye, Ya Fatou; Kulkarni, Madhura; Opere, Catherine A.; Ohia, Sunny E. Experimental Eye Research vol. 98 May, 2012. p. 16-22

 Hydrogen sulfide (H2S), a colorless gas with the pungent odor of rotten eggs… (more)

Keywords: hydrogen sulfide; cyclic AMP; retinal pigmented epithelial cells; H2S; hydrogen sulfide; NaHS; sodium hydrosulfide; AOA; aminooxyacetic acid; PAG; proparglyglycine; RPE-J; rat retinal pigment epithelial; cyclic AMP; adenosine 3′, 5′ cyclic monophosphate; COX; cyclooxygenase; CSE; cystathionine γ-lyase; CBS; cystathionine β-synthase

DOI: 10.1016/j.exer.2012.03.001. ISSN: 0014-4835.

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21. Pharmacological actions of the slow release hydrogen sulfide donor GYY4137 on phenylephrine-induced tone in isolated bovine ciliary artery. Chitnis, Madhura Kulkarni; Njie-Mbye, Ya Fatou; Opere, Catherine A.; Wood, Mark E.; Whiteman, Matthew; Ohia, Sunny E. Experimental Eye Research vol. 116 November, 2013. p. 350-354

 Hydrogen sulfide (H2S), a colorless gas characterized by its pungent odor of rotten… (more)

Keywords: hydrogen sulfide; GYY4137; bovine posterior ciliary artery; prostanoids; cystathionine β-synthase; cystathionine γ-lyase; PCA; posterior ciliary arteries; COX; cyclo-oxygenase; H2S; hydrogen sulfide; CBS; cystathionine β-synthase; CSE; cystathionine γ-lyase; NaSH; sodium hydrosulfide; PAG; propargylglycine; AOAA; aminooxyacetic acid; SAM; S-adenosyl-l-methionine; l-NAME; l-nitroarginine methyl ester

DOI: 10.1016/j.exer.2013.10.004. ISSN: 0014-4835.

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