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1. Tuberous sclerosis: Localizing the epileptogenic tuber with synthetic aperture magnetometry with excess kurtosis analysis. Canuet, Leonides; Ishii, Ryouhei; Iwase, Masao; Kurimoto, Ryu; Ikezawa, Koji; Azechi, Michiyo; Wataya-Kaneda, Mari; Takeda, Masatoshi. Journal of Clinical Neuroscience vol. 15 issue 11 November, 2008. p. 1296-1298

 The hallmark of tuberous sclerosis is the presence of multiple cortical tubers. Identifying… (more)

Keywords: Tuberous sclerosis; Magnetoencephalography; Synthetic aperture magnetometry; Kurtosis; Epileptogenic tuber

DOI: 10.1016/j.jocn.2007.03.030. ISSN: 0967-5868.

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2. 75. MEG activities during a memory task in patients with early Alzheimer’s disease and mild cognitive impairment. Kurimoto, Ryu; Ishii, Ryouhei; Canuet, Leonides; Ikezawa, Koji; Iwase, Masao; Kazui, Hiromitsu; Yoshimine, Toshiki; Takeda, Masatoshi. Clinical Neurophysiology vol. 119 issue 6 June, 2008. p. e93

DOI: 10.1016/j.clinph.2008.01.100. ISSN: 1388-2457.

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3. Cortical oscillatory power changes during auditory oddball task revealed by spatially filtered magnetoencephalography. Ishii, Ryouhei; Canuet, Leonides; Herdman, Anthony; Gunji, Atsuko; Iwase, Masao; Takahashi, Hidetoshi; Nakahachi, Takayuki; Hirata, Masayuki; Robinson, Stephen E.; Pantev, Christo; Takeda, Masatoshi. Clinical Neurophysiology vol. 120 issue 3 March, 2009. p. 497-504

 ObjectiveTo investigate the neural sources and associated changes in oscillatory activity involved in… (more)

Keywords: P300; Event-related synchronization (ERS); Oscillatory activity; Prefrontal cortex; Magnetoencephalography (MEG); Synthetic aperture magnetometry (SAM)

DOI: 10.1016/j.clinph.2008.11.023. ISSN: 1388-2457.

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4. 36. Alpha and beta ERD in a visual memory task in patients with Alzheimer’s disease and mild cognitive impairment. Kurimoto, Ryu; Ishii, Ryouhei; Ikezawa, Koji; Canuet, Leonides; Iwase, Masao; Azechi, Michiyo; Kazui, Hiroaki; Yoshimine, Toshiki; Takeda, Masatoshi. Clinical Neurophysiology vol. 120 issue 5 May, 2009. p. e155

DOI: 10.1016/j.clinph.2009.02.042. ISSN: 1388-2457.

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5. 63. Abnormal brain oscillatory changes between eye-open and eye-closed resting condition in schizophrenia. Ikezawa, Koji; Ishii, Ryouhei; Kurimoto, Ryu; Canuet, Leonides; Iwase, Masao; Takahashi, Hidetoshi; Nakahachi, Takayuki; Azechi, Michiyo; et al. Clinical Neurophysiology vol. 120 issue 5 May, 2009. p. e161

DOI: 10.1016/j.clinph.2009.02.069. ISSN: 1388-2457.

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6. 97. Correlation analysis in healthy controls during digit symbol substitution test: A NIRS study. Ishii, Ryouhei; Nakahachi, Takayuki; Iwase, Masao; Takahashi, Hidetoshi; Kurimoto, Ryu; Ikezawa, Koji; Canuet, Leonides; Azechi, Michiyo; Takeda, Masatoshi. Clinical Neurophysiology vol. 120 issue 5 May, 2009. p. e169

DOI: 10.1016/j.clinph.2009.02.103. ISSN: 1388-2457.

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7. 149. Electroencephalography neuroimaging of oscillatory activity in chronic interictal psychosis of epilepsy. Canuet, Leonides; Ishii, Ryouhei; Kurimoto, Ryu; Iwase, Masao; Ikezawa, Koji; Azechi, Michiyo; Takahashi, Hidetoshi; Nakahachi, Takayuki; Takeda, Masatoshi. Clinical Neurophysiology vol. 120 issue 5 May, 2009. p. e180

DOI: 10.1016/j.clinph.2009.02.155. ISSN: 1388-2457.

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8. 21. Time course of frontal lobe activation in schizophrenia: A multi-task study using two channel near-infrared spectroscopy. Iwase, Masao; Azechi, Michiyo; Ikezawa, Koji; Ishii, Ryouhei; Takahashi, Hidetoshi; Nakahachi, Takayuki; Canuet, Leonides; Kurimoto, Ryu; et al. Clinical Neurophysiology vol. 121 issue 7 July, 2010. p. e24

DOI: 10.1016/j.clinph.2010.02.102. ISSN: 1388-2457.

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9. Cephalic auras of supplementary motor area origin: An ictal MEG and SAM(g2) study. Canuet, Leonides; Ishii, Ryouhei; Iwase, Masao; Kurimoto, Ryu; Ikezawa, Kouji; Azechi, Michiyo; Takahashi, Hidetoshi; Nakahachi, Takayuki; Takeda, Masatoshi. Epilepsy and Behavior vol. 13 issue 3 October, 2008. p. 570-574

 Although a nonspecific cephalic sensation, the so-called “cephalic aura,” is a common sensory… (more)

Keywords: Cephalic aura; Sensory seizure; Supplementary motor area; Frontal lobe epilepsy; Ictal magnetoencephalography; Electroencephalography; Synthetic aperture magnetometry; Kurtosis

DOI: 10.1016/j.yebeh.2008.05.013. ISSN: 1525-5050.

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10. Working memory abnormalities in chronic interictal epileptic psychosis and schizophrenia revealed by magnetoencephalography. Canuet, Leonides; Ishii, Ryouhei; Iwase, Masao; Ikezawa, Koji; Kurimoto, Ryu; Takahashi, Hidetoshi; Currais, Antonio; Azechi, Michiyo; Nakahachi, Takayuki; Hashimoto, Ryota; Takeda, Masatoshi. Epilepsy and Behavior vol. 17 issue 1 January, 2010. p. 109-119

 Working memory (WM) deficits are considered a core cognitive dysfunction in schizophrenia. To… (more)

Keywords: Epilepsy; Interictal psychosis; Schizophrenia; Working memory; Cognitive deficits; Alpha oscillations; Magnetoencephalography

DOI: 10.1016/j.yebeh.2009.11.002. ISSN: 1525-5050.

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11. Slow repetitive transcranial magnetic stimulation changes oscillatory magnetoencephalographic activity in two patients with thalamic pain. Kurimoto, Ryu; Ishii, Ryouhei; Canuet, Leonides; Iwase, Masao; Sekiyama, Ryuji; Takahashi, Kiyotake; Nakahachi, Takayuki; Ukai, Satoshi; Shinosaki, Kazuhiro; Takeda, Masatoshi. International Congress Series vol. 1300 June, 2007. p. 295-298

 To evaluate the effects of slow repetitive transcranial magnetic stimulation (rTMS) on thalamic… (more)

Keywords: Repetitive transcranial magnetic stimulation (rTMS); Magnetoencephalography (MEG); Thalamic pain; Brain plasticity

DOI: 10.1016/j.ics.2006.12.065. ISSN: 0531-5131.

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12. Severity of depressive symptoms as predictor of impairment of quality of life in chronic migraine: Comparison with episodic migraine. Canuet, Leonides; Ishii, Ryouhei; Fernandez-Concepcion, Otman; Iwase, Masao; Takeda, Masatoshi. Psychiatry and Clinical Neurosciences vol. 62 issue 6 December 2008. p. 738-740

  To identify predictors of quality of life (QoL) in episodic migraine (EM)… (more)

Keywords: chronic migraine; depression; Headache Needs Assessment; quality of life

DOI: 10.1111/pcn.2008.62.issue-6. ISSN: 1323-1316.

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13. Psychopathology and working memory-induced activation of the prefrontal cortex in schizophrenia-like psychosis of epilepsy: Evidence from magnetoencephalography. Canuet, Leonides; Ishii, Ryouhei; Iwase, Masao; Ikezawa, Koji; Kurimoto, Ryu; Takahashi, Hidetoshi; Currais, Antonio; Azechi, Michiyo; Aoki, Yasunori; Nakahachi, Takayuki; Soriano, Salvador; Takeda, Masatoshi. Psychiatry and Clinical Neurosciences vol. 65 issue 2 March 2011. p. 183-190

  Aim:  The aim of this study was to investigate whether magnetoencephalographic oscillations… (more)

Keywords: epilepsy; magnetoencephalography; prefrontal cortex; schizophrenia; working memory

DOI: 10.1111/j.1440-1819.2010.02179.x. ISSN: 1323-1316.

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14. Caffeine Modulates Tau Phosphorylation and Affects Akt Signaling in Postmitotic Neurons. Currais, Antonio; Kato, Kiyoko; Canuet, Leonides; Ishii, Ryouhei; Tanaka, Toshihisa; Takeda, Masatoshi; Soriano, Salvador. Journal of Molecular Neuroscience vol. 43 issue 3 March 2011. p. 326 - 332

  Neuronal cell cycle reentry, which is associated with aberrant tau phosphorylation, is… (more)

Keywords: Neurodegeneration; Alzheimer’s; Tau; Caffeine; Cell cycle; Akt

DOI: 10.1007/s12031-010-9444-8. ISSN: 0895-8696.

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15. Impaired regional hemodynamic response in schizophrenia during multiple prefrontal activation tasks: A two-channel near-infrared spectroscopy study. Ikezawa, Koji; Iwase, Masao; Ishii, Ryouhei; Azechi, Michiyo; Canuet, Leonides; Ohi, Kazutaka; Yasuda, Yuka; Iike, Naomi; et al. Schizophrenia Research vol. 108 issue 1-3 March, 2009. p. 93-103

 In schizophrenia, dysfunction of the prefrontal cortex (PFC), regarded as a core feature… (more)

Keywords: Schizophrenia; Near-infrared spectroscopy (NIRS); Frontal lobe dysfunction; Physiological marker

DOI: 10.1016/j.schres.2008.12.010. ISSN: 0920-9964.

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16. Relationship between prepulse inhibition of acoustic startle response and schizotypy in healthy Japanese subjects. Takahashi, Hidetoshi; Iwase, Masao; Canuet, Leonides; Yasuda, Yuka; Ohi, Kazutaka; Fukumoto, Motoyuki; Iike, Naomi; Nakahachi, Takayuki; et al. Psychophysiology vol. 47 issue 5 September 2010. p. 831-837

  Abstract Prepulse inhibition (PPI) of the acoustic startle reflex (ASR) is the… (more)

Keywords: Prepulse inhibition; Sensorimotor gating; Schizotypy; Acoustic startle response; Asians

DOI: 10.1111/j.1469-8986.2010.01000.x. ISSN: 0048-5772.

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17. Factors associated with impaired quality of life in younger and older adults with epilepsy. Canuet, Leonides; Ishii, Ryouhei; Iwase, Masao; Ikezawa, Koji; Kurimoto, Ryu; Azechi, Michiyo; Takahashi, Hidetoshi; Nakahachi, Takayuki; Teshima, Yoshio; Takeda, Masatoshi. Epilepsy Research vol. 83 issue 1 January, 2009. p. 58-65

 SummaryThe purpose of this study is to weigh psychological state, patients’ demographics, seizure-related… (more)

Keywords: Quality of life; Elderly; Epilepsy; Depression

DOI: 10.1016/j.eplepsyres.2008.09.001. ISSN: 0920-1211.

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18. Spatially filtered magnetoencephalography compared with electrocorticography to identify intrinsically epileptogenic focal cortical dysplasia. Ishii, Ryouhei; Canuet, Leonides; Ochi, Ayako; Xiang, Jing; Imai, Katsumi; Chan, Derrick; Iwase, Masao; Takeda, Masatoshi; Snead, O. Carter; Otsubo, Hiroshi. Epilepsy Research vol. 81 issue 2-3 October, 2008. p. 228-232

 SummaryThis study was carried out to evaluate Synthetic Aperture Magnetometry-kurtosis (SAM(g2)), a spatially… (more)

Keywords: Epilepsy; Focal cortical dysplasia (FCD); Electrocorticography (ECoG); Magnetoencephalography (MEG); Synthetic Aperture Magnetometry-kurtosis (SAM(g2))

DOI: 10.1016/j.eplepsyres.2008.06.006. ISSN: 0920-1211.

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19. Event-related synchronization of alpha activity in early Alzheimer’s disease and mild cognitive impairment: An MEG study combining beamformer and group comparison. Kurimoto, Ryu; Ishii, Ryouhei; Canuet, Leonides; Ikezawa, Koji; Azechi, Michiyo; Iwase, Masao; Yoshida, Tetsuhiko; Kazui, Hiromitsu; Yoshimine, Toshiki; Takeda, Masatoshi. Neuroscience Letters vol. 443 issue 2 October 3, 2008. p. 86-89

 In patients with Alzheimer’s disease (AD), it is sometimes challenging to identify typical… (more)

Keywords: Magnetoencephalography; Event-related synchronization; Alzheimer’s disease; Mild cognitive impairment; Beamformer; Group comparison

DOI: 10.1016/j.neulet.2008.07.015. ISSN: 0304-3940.

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20. Heartbeat evoked potentials: A new possible clinical biomarker for depression based on the somatic marker hypothesis. Ishii, Ryouhei; Canuet, Leonides. Clinical Neurophysiology vol. 123 issue 10 October, 2012. p. 1899-1900

DOI: 10.1016/j.clinph.2012.03.002. ISSN: 1388-2457.

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21. EEG connectome: A new candidate for endophenotypes. Ishii, Ryouhei; Canuet, Leonides. Clinical Neurophysiology vol. 124 issue 12 December, 2013. p. 2289-2290

DOI: 10.1016/j.clinph.2013.07.011. ISSN: 1388-2457.

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22. Global complexity and cognitive reserve in MCI. Ishii, Ryouhei; Canuet, Leonides. Clinical Neurophysiology vol. 125 issue 4 April, 2014. p. 653-654

DOI: 10.1016/j.clinph.2013.10.015. ISSN: 1388-2457.

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